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le 01/09/00  |
Volume 32, Issue 4, October 2000
HEPATOLOGY HIGHLIGHTS
ORIGINAL ARTICLES
CHRONIC
LIVER DISEASE
GROWTH
REGULATION AND CANCER
INFLAMMATION,
CYTOKINES, AND FIBROSIS
LIVER
CELL INJURY AND APOPTOSIS
METABOLISM,
TRANSPORT, AND GENETIC DISEASES
MOLECULAR
CELL BIOLOGY
VIRAL
HEPATITIS
HEPATOLOGY CLINICAL CHALLENGE
EDITORIALS
HEPATOLOGY ELSEWHERE
CORRESPONDENCE
CORRECTIONS
Highlights from this Issue
James L. Boyer
Hepatology 2000 32: 687-688.
Original Articles
Chronic Liver Disease
Prevalence of Obesity and Diabetes in Patients With Cryptogenic
Cirrhosis: A Case-Control Study (·Human Study·)
Asma Poonawala, Satheesh P. Nair, and Paul J. Thuluvath
Hepatology 2000 32: 689-692. [Abstract]
Liver Transplantation for Autoimmune Hepatitis
(·Human Study·)
David J. Reich, Isabel Fiel, James V. Guarrera, Sukru Emre, Stephen
R. Guy, Myron E. Schwartz, Charles M. Miller, and Patricia A.
Sheiner
Hepatology 2000 32: 693-700.
[Abstract]
Growth Regulation and Cancer
Loss of Nuclear p53 Protein in Preneoplastic Rat Hepatocytes
Is Accompanied by Mdm2 and Bcl-2 Overexpression and by Defective
Response to DNA Damage In Vivo
Hilde E. Van Gijssel, Lena C. E. Ohlson, Ulla-Britta Torndal,
Gerard J. Mulder, Lennart C. Eriksson, Inger Porsch-Hällström,
and John H. N. Meerman
Hepatology 2000 32: 701-710.
[Abstract]
Hepatocellular Carcinoma Cell Cycle: Study of Long-Evans
Cinnamon Rats
Tsutomu Masaki, Yasushi Shiratori, William Rengifo, Kouichi Igarashi,
Kouzou Matsumoto, Mikio Nishioka, Yoshio Hatanaka, and Masao Omata
Hepatology 2000 32: 711-720. [Abstract]
Identification of the Gene for a Novel Liver-Related Putative
Tumor Suppressor at a High-Frequency Loss of Heterozygosity Region
of Chromosome 8p23 in Human Hepatocellular Carcinoma
(·Human Study·)
Cheng Liao, Mujun Zhao, Hai Song, Kiyoshi Uchida, Kazunari K.
Yokoyama, and Tsaiping Li
Hepatology 2000 32: 721-727.
[Abstract]
Inflammation, Cytokines, and Fibrosis
Murine Concanavalin A-Induced Hepatitis Is Prevented by
Interleukin 12 (IL-12) Antibody and Exacerbated by Exogenous IL-12
Through an Interferon--Dependent Mechanism
Ferdinando Nicoletti, Roberto Di Marco, Paola Zaccone, Antonio
Salvaggio, Gaetano Magro, Klaus Bendtzen, and PierLuigi Meroni
Hepatology 2000 32: 728-733.
[Abstract]
The Systemic Inflammatory Response Syndrome in Acute Liver
Failure (·Human Study·)
Nancy Rolando, Jim Wade, Milagros Davalos, Julia Wendon, John
Philpott-Howard, and Roger Williams
Hepatology 2000 32: 734-739.
[Abstract]
Liver Cell Injury and Apoptosis
-Glutamyltranspeptidase-Deficient Knockout Mice as a Model
to Study the Relationship Between Glutathione Status, Mitochondrial
Function, and Cellular Function
Yvonne Will, Kay A. Fischer, Robert A. Horton, Rhonda S. Kaetzel,
Marda K. Brown, Olaf Hedstrom, Michael W. Lieberman, and Donald
J. Reed
Hepatology 2000 32: 740-749. [Abstract]
Transforming Growth Factor-1 Induces Apoptosis in
Rat FaO Hepatoma Cells Via Cytochrome c Release and Oligomerization
of Apaf-1 to Form a ~700-kd Apoptosome Caspase-Processing Complex
Caroline Freathy, David G. Brown, Ruth A. Roberts, and Kelvin
Cain
Hepatology 2000 32: 750-760. [Abstract]
Up-regulation of Fas Ligand at Early Stages and Down-regulation
of Fas at Progressed Stages of Intrahepatic Cholangiocarcinoma
Reflect Evasion From Immune Surveillance (·Human
Study·)
Tomonori Shimonishi, Kumiko Isse, Fumie Shibata, Isao Aburatani,
Koichi Tsuneyama, Hemragul Sabit, Kenichi Harada, Kohji Miyazaki,
and Yasuni Nakanuma
Hepatology 2000 32: 761-769. [Abstract]
Nitric Oxide Prevents Tumor Necrosis Factor -Induced Rat
Hepatocyte Apoptosis by the Interruption of Mitochondrial Apoptotic
Signaling Through S-Nitrosylation of Caspase-8
Young-Myeong Kim, Tae-Hyoung Kim, Hun-Taeg Chung, Robert V. Talanian,
Xiao-Ming Yin, and Timothy R. Billiar
Hepatology 2000 32: 770-778. [Abstract]
Induction of Murine Hepatocyte Death by Membrane-Bound CD95
(Fas/APO-1)-Ligand: Characterization of an In Vitro System
Stephan F. Schlosser, Francesco Azzaroli, Tao Dao, Ravi Hingorani,
I. Nicholas Crispe, and James L. Boyer
Hepatology 2000 32: 779-785. [Abstract]
Metabolism, Transport, and Genetic Diseases
Shear Stress Modulates the Vascular Tone in Perfused Livers
Isolated From Normal Rats
Catherine M. Pastor and Antoine Hadengue
Hepatology 2000 32: 786-791. [Abstract]
Molecular Diagnosis of a Familial Nonhemolytic Hyperbilirubinemia
(Gilbert's Syndrome) in Healthy Subjects (·Human
Study·)
Jürgen Borlak, Thomas Thum, Olfert Landt, Katharina Erb,
and Robert Hermann
Hepatology 2000 32: 792-795. [Abstract]
Molecular Cell Biology
Hepatocyte Growth Factor Promotes Cell Survival From Fas-Mediated
Cell Death in Hepatocellular Carcinoma Cells via Akt Activation
and Fas-Death-Inducing Signaling Complex Suppression
(·Human Study·)
Atsushi Suzuki, Midori Hayashida, Hirokazu Kawano, Kazushi Sugimoto,
Takeshi Nakano, and Katsuya Shiraki
Hepatology 2000 32: 796-802.
[Abstract]
Viral Hepatitis
Hepatitis B e Antigen Seroconversion After Lamivudine Therapy
Is Not Durable in Patients With Chronic Hepatitis B in Korea
(·Human Study·)
Byung-Cheol Song, Dong Jin Suh, Han Chu Lee, Young-Hwa Chung,
and Yung Sang Lee
Hepatology 2000 32: 803-806.
[Abstract]
Temporal Pathogenesis of Experimental Neonatal Woodchuck
Hepatitis Virus Infection: Increased Initial Viral Load and Decreased
Severity of Acute Hepatitis During the Development of Chronic
Viral Infection
Paul J. Cote, Ilia Toshkov, Christine Bellezza, Mary Ascenzi,
Carol Roneker, Lou Ann Graham, Betty H. Baldwin, Karen Gaye, Ikuo
Nakamura, Brent E. Korba, Bud C. Tennant, and John L. Gerin
Hepatology 2000 32: 807-817. [Abstract]
Detection of Residual Hepatitis C Virus RNA by Transcription-Mediated
Amplification in Patients With Complete Virologic Response According
to Polymerase Chain Reaction-Based Assays (·Human
Study·)
Christoph Sarrazin, Gerlinde Teuber, Robert Kokka, Holger Rabenau,
and Stefan Zeuzem
Hepatology 2000 32: 818-823. [Abstract]
Chronic Hepatitis D: A Vanishing Disease? An Italian Multicenter
Study (·Human Study·)
Giovanni B. Gaeta, Tommaso Stroffolini, Maria Chiaramonte, Tiziana
Ascione, Gianfranca Stornaiuolo, Salvatore Lobello, Evangelista
Sagnelli, Maurizia R. Brunetto, and Mario Rizzetto
Hepatology 2000 32: 824-827.
[Abstract]
Long-Term Therapy of Chronic Hepatitis B With Lamivudine
(·Human Study·)
Daryl T.-Y. Lau, M. Farooq Khokhar, Edward Doo, Marc G. Ghany,
David Herion, Yoon Park, David E. Kleiner, Peter Schmid, Lynn
D. Condreay, Josée Gauthier, Mary C. Kuhns, T. Jake Liang,
and Jay H. Hoofnagle
Hepatology 2000 32: 828-834. [Abstract]
Randomized, Double-Blind, Placebo-Controlled Trial of Interferon
Alfa2a With and Without Amantadine as Initial Treatment for Chronic
Hepatitis C (·Human Study·)
Stefan Zeuzem, Gerlinde Teuber, Uta Naumann, Thomas Berg, Jochen
Raedle, Susanne Hartmann, and Uwe Hopf
Hepatology 2000 32: 835-841. [Abstract]
Screening for Hepatocellular Carcinoma in Alaska Natives
Infected With Chronic Hepatitis B: A 16-Year Population-Based
Study (·Human Study·) Brian J.
McMahon, Lisa Bulkow, Annette Harpster, Mary Snowball, Anne Lanier,
Frank Sacco, Eitel Dunaway, and James Williams
Hepatology 2000 32: 842-846.
[Abstract]
Efficacy of Long-Term Lamivudine Monotherapy in Patients
With Hepatitis B e Antigen-Negative Chronic Hepatitis B
(·Human Study·)
Stephanos J. Hadziyannis, George V. Papatheodoridis, Evangelini
Dimou, Andreas Laras, and Christos Papaioannou
Hepatology 2000 32: 847-851.
[Abstract]
Natural History of Clinically Compensated Hepatitis C Virus-Related
Graft Cirrhosis After Liver Transplantation (·Human
Study·)
Marina Berenguer, Martín Prieto, José M. Rayón,
Julio Mora, Miguel Pastor, Vicente Ortiz, Domingo Carrasco, Fernando
San Juan, Manuel-de-Juan Burgueño, José Mir, and
Joaquín Berenguer
Hepatology 2000 32: 852-858.
[Abstract]
ALIMENTARY TRACT:
A Multicenter Trial of 6-Mercaptopurine and Prednisone in
Children With Newly Diagnosed Crohn's Disease
JAMES MARKOWITZ, KATHY GRANCHER, NINA KOHN, MARTIN LESSER, FREDRIC
DAUM, and THE PEDIATRIC 6MP COLLABORATIVE GROUP Gastroenterology
2000 119: 895-902. Published online Oct 19 2000.
[Abstract]
Comparison of Heparin and Steroids in the Treatment of Moderate
and Severe Ulcerative Colitis
JULIÁN PANÉS, MARIA ESTEVE, EDUARD CABRÉ,
JOAQUÍN HINOJOSA, MONTSERRAT ANDREU, MIQUEL SANS, FERNANDO
FERNANDEZ-BAÑARES, FAUST FEU, MIQUEL A. GASSULL, and JOSEP
M. PIQUÉ
Gastroenterology 2000 119: 903-908. Published online Oct 19 2000.
[Abstract]
Genetic Factors Determine Extent of Bone Loss in Inflammatory
Bowel Disease
CLAUDIA M. S. SCHULTE, AXEL U. DIGNASS, HARALD GOEBELL, HANS-DIETRICH
RÖHER, and KLAUS-MARTIN SCHULTE
Gastroenterology 2000 119: 909-920. Published online Oct 19 2000.
[Abstract]
Microsatellite Instability Is a Favorable Prognostic Indicator
in Patients With Colorectal Cancer Receiving Chemotherapy
AKSELI HEMMINKI, JUKKA-PEKKA MECKLIN, HEIKKI JÄRVINEN, LAURI
A. AALTONEN, and HEIKKI JOENSUU
Gastroenterology 2000 119: 921-928. Published online Oct 19 2000.
[Abstract]
p16INK4a Expression Begins Early in Human Colon Neoplasia
and Correlates Inversely With Markers of Cell Proliferation
CHARLOTTE Y. DAI, EMMA E. FURTH, ROSEMARIE MICK, JIM KOH, TETSUJI
TAKAYAMA, YOSHIRO NIITSU, and GREG H. ENDERS
Gastroenterology 2000 119: 929-942. Published online Oct 19 2000.
[Abstract]
The Effects of Intestinal Infusion of Long-Chain Fatty Acids
on Food Intake in Humans
STEPHEN J. FRENCH, CATHRYN A. CONLON, SANDRA T. MUTUMA, MYRTHA
ARNOLD, NICK W. READ, GERT MEIJER, and JOHN FRANCIS
Gastroenterology 2000 119: 943-948. Published online Oct 19 2000.
[Abstract]
The Specific Activities of Human Digestive Lipases Measured
From the In Vivo and In Vitro Lipolysis of Test Meals
FRÉDÉRIC CARRIÈRE, CHRISTOPHE RENOU, VÉRONIQUE
LOPEZ, JOSIANE DE CARO, FRANCINE FERRATO, HANS LENGSFELD, ALAIN
DE CARO, RENÉ LAUGIER, and ROBERT VERGER
Gastroenterology 2000 119: 949-960. Published online Oct 19 2000.
[Abstract]
Cdx1 and Cdx2 Expression During Intestinal Development
DEBRA G. SILBERG, GARY P. SWAIN, EUN RAN SUH, and PETER G. TRABER
Gastroenterology 2000 119: 961-971. Published online Oct 19 2000.
[Abstract]
Interleukin 16 Is Up-regulated in Crohn's Disease and Participates
in TNBS Colitis in Mice
ANDREW C. KEATES, IGNAZIO CASTAGLIUOLO, WILLIAM W. CRUICKSHANK,
BOSHENG QIU, KRISTEN O. ARSENEAU, WILLIAM BRAZER, and CIARÁN
P. KELLY Gastroenterology 2000 119: 972-982. Published online
Oct 19 2000. [Abstract]
Limited CD4 T-Cell Diversity Associated With Colitis in
T-Cell Receptor Mutant Mice Requires a T Helper 2 Environment
ATSUSHI MIZOGUCHI, EMIKO MIZOGUCHI, LAWRENCE J. SAUBERMANN, KOICHI
HIGAKI, RICHARD S. BLUMBERG, and ATUL K. BHAN
Gastroenterology 2000 119: 983-995. Published online Oct 19 2000.
[Abstract]
Interleukin 15 Mediates Epithelial Changes in Celiac Disease
LUIGI MAIURI, CAROLINA CIACCI, SALVATORE AURICCHIO, VIRGINIA BROWN,
SONIA QUARATINO, and MARCO LONDEI
Gastroenterology 2000 119: 996-1006. Published online Oct 19 2000.
[Abstract]
Leukotrienes Induce Cell-Survival Signaling in Intestinal
Epithelial Cells
JOHN F. ÖHD, KATARINA WIKSTRÖM, and ANITA SJÖLANDER
Gastroenterology 2000 119: 1007-1018. Published online Oct 19
2000.
[Abstract]
Environmental Stress-Induced Gastrointestinal Permeability
Is Mediated by Endogenous Glucocorticoids in the Rat
JON B. MEDDINGS and M. G. SWAIN
Gastroenterology 2000 119: 1019-1028. Published online Oct 19
2000. [Abstract]
Permeability of the Rat Small Intestinal Epithelium Along
the Villus-Crypt Axis: Effects of Glucose Transport
BRITT-MARIE FIHN, ANDERS SJÖQVIST, and MATS JODAL
Gastroenterology 2000 119: 1029-1036. Published online Oct 19
2000. [Abstract]
Neurokinin 1 and 2 Receptors Mediate Cholera Toxin Secretion
in Rat Jejunum
JAMES L. TURVILL, PATRICK CONNOR, and MICHAEL J. G. FARTHING
Gastroenterology 2000 119: 1037-1044. Published online Oct 19
2000. [Abstract]
E-cadherin and Adenomatous Polyposis Coli
Mutations Are Synergistic in Intestinal Tumor Initiation in Mice
RON SMITS, PATRICIA RUIZ, SALVADOR DIAZ-CANO, ARNE LUZ, SHANTIE
JAGMOHAN-CHANGUR, COR BREUKEL, CARMEN BIRCHMEIER, WALTER BIRCHMEIER,
and RICCARDO FODDE
Gastroenterology 2000 119: 1045-1053. Published online Oct 19
2000. [Abstract]
Orphanin FQ Causes Contractions via Inhibiting Purinergic
Pathway in the Rat Colon
TOKU TAKAHASHI, DIDIER BAGNOL, DAVID SCHNEIDER, YOHEI MIZUTA,
TADASHI ISHIGUCHI, KATHY LePARD, JAMES J. GALLIGAN, STANLEY J.
WATSON, and CHUNG OWYANG Gastroenterology 2000 119: 1054-1063.
Published online Oct 19 2000. [Abstract]
LIVER, PANCREAS, AND BILIARY TRACT:
Hepatitis Virus Infections in Heart Transplant Recipients:
Epidemiology, Natural History, Characteristics, and Impact on
Survival
FRANÇOISE LUNEL, JEAN-FRANÇOIS CADRANEL, MICHEL
ROSENHEIM, RICHARD DORENT, VINCENT DI-MARTINO, CHRISTOPHER PAYAN,
CATHERINE FRETZ, JEAN-JACQUES GHOUSSOUB, BRIGITTE BERNARD, BRUNO
DUMONT, MICHÈLE PERRIN, IRANJ GANDJBACHKH, JEAN MARIE HURAUX,
LIEVEN STUYVER, and PIERRE OPOLON
Gastroenterology 2000 119: 1064-1074. Published online Oct 19
2000.
[Abstract]
Differential HFE Allele Expression in Hemochromatosis Heterozygotes
OLIVIER ROSMORDUC, RAOUL POUPON, ISABELLE NION, DOMINIQUE WENDUM,
JOHN FEDER, GILBERT BÉRÉZIAT, and BRIGITTE HERMELIN
Gastroenterology 2000 119: 1075-1086. Published online Oct 19
2000. [Abstract]
Pancreatic Involvement in von Hippel-Lindau Disease
PASCAL R. HAMMEL, VALERIE VILGRAIN, BENOIT TERRIS, ALFRED PENFORNIS,
ALAIN SAUVANET, JEAN-MICHEL CORREAS, DOMINIQUE CHAUVEAU, AXEL
BALIAN, CATHERINE BEIGELMAN, DERMOT O'TOOLE, PIERRE BERNADES,
PHILIPPE RUSZNIEWSKI, STEPHANE RICHARD, and THE GROUPE FRANCOPHONE
d'ETUDE DE LA MALADIE DE VON HIPPEL-LINDAU
Gastroenterology 2000 119: 1087-1095. Published online Oct 19
2000. [Abstract]
Circulating Soluble Vascular Adhesion Protein 1 Accounts
for the Increased Serum Monoamine Oxidase Activity in Chronic
Liver Disease
RIIKKA KURKIJÄRVI, GENNADY G. YEGUTKIN, BRIDGET K. GUNSON,
SIRPA JALKANEN, MARKO SALMI, and DAVID H. ADAMS
Gastroenterology 2000 119: 1096-1103. Published online Oct 19
2000. [Abstract]
Mouse -Fetoprotein-Specific DNA-Based Immunotherapy of Hepatocellular
Carcinoma Leads to Tumor Regression in Mice
CHRISTIAN F. GRIMM, DÖRTE ORTMANN, LEONHARD MOHR, SABINE
MICHALAK, TIM U. KROHNE, STEPHAN MECKEL, SILKE EISELE, JENS ENCKE,
HUBERT E. BLUM, and MICHAEL GEISSLER
Gastroenterology 2000 119: 1104-1112. Published online Oct 19
2000. [Abstract]
Molecular Identification and Functional Characterization
of Mdr1a in Rat Cholangiocytes
ALESSANDRO GIGLIOZZI, FLAVIA FRAIOLI, PAZHANI SUNDARAM, JOHN LEE,
ALBERT MENNONE, DOMENICO ALVARO, and JAMES L. BOYER
Gastroenterology 2000 119: 1113-1122. Published online Oct 19
2000. [Abstract]
Kinesin Is Involved in Regulation of Rat Pancreatic Amylase
Secretion
NAMIKI UEDA, HIROHIDE OHNISHI, CHIHO KANAMARU, JUNKO SUZUKI, TOMOHIRO
TSUCHIDA, HIROSATO MASHIMA, HIROSHI YASUDA, and TOSHIRO FUJITA
Gastroenterology 2000 119: 1123-1131. Published online Oct 19
2000.
[Abstract]
ABC of colorectal cancer: Molecular basis for risk factors
Robert G Hardy, Stephen J Meltzer, and Janusz A Jankowski
BMJ 2000; 321: 886-889.
[Full text]
ABC of colorectal cancer: The role of clinical genetics
in management
T R P Cole and H V Sleightholme
BMJ 2000; 321: 943-946. [Full
text]
Can we improve diagnosis of acute appendicitis?
Spencer W Beasley
BMJ 2000; 321: 907-908.
[Full text]
Rectal bleeding and colorectal cancer in general practice:
diagnostic study
Hans Wauters, Viviane Van Casteren, and Frank Buntinx
BMJ 2000;321 998-999
[Full text]
ABC of colorectal cancer: Screening
John H Scholefield
BMJ 2000;321 1004-1006 [Full
text]
Hepatitis C victims sue NHS in class action
Clare Dyer
BMJ 2000;321 978 [Full
text]
Tampons could be used to diagnose STDs
Scott Gottlieb
BMJ 2000;321 978
[Full text]
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