Lactocoques GMOs producteurs d ’IL-10 Steidler L et coll. Science 2000 25;289(5483):1352-5
Lactococcus lactis genetically engineered to secrete IL-10
Intragastric administration of IL-10-secreting L. lactis
--> 50% reduction in colitis in mice treated with dextran sulfate sodium
--> prevented the onset of colitis in IL-10(-/-) mice