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What role does H. pylori have in ‘acid-NSAID disease’?
H. pylori infection and the use of nonsteroidal anti-inflammatory drugs (NSAID) are both known to cause peptic ulceration, but it is not yet clear whether they have a synergistic role. If this is the case, then eradicating the bacterium in H. pylori-posit
However, eradication of H. pylori in NSAID users may remove a known risk factor for peptic ulceration and, thus, be justified. In addition, two large international, pivotal studies have shown that omeprazole, 20 mg daily, provides rapid symptom resolution
